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Force ductility of asphalt binders
Smolka, Zdeněk ; Coufalík, Pavel (referee) ; Dašek, Ondřej (advisor)
The bachelor thesis describes a laboratory characteristics of bituminous binders. There will be described the principle and results of laboratory tests, needle penetration, softening point by ring and ball and force ductility. The tests will be performed on samples of the bituminous binders with different degrees of modification.
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Evaluation of Nuclear Fuel Safety and Reliability Using Research Reactors' In-Core Experiments
Matocha, Vítězslav ; Foral, Štěpán (referee) ; Katovský, Karel (advisor)
The aim of this master thesis is to show a connection among nuclear fuel safety, experiments led in research reactors and calculation codes. This thesis focuses on the calculation code Transuranus. There are represented four experiments, which were calculated in Transuranus. The fission gas release, elongation and growth of fuel were particularly monitored. Is is possible to set differences among versions v1m1j09 and v1m3j12 from achieved results, as well as the influence of selected Transuranus parameters on the results, so the thesis may bring new pieces of knowledge for improvement of safety analysis calculation by Transuranus.
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Role of translational elongation factors in dynamics of stress granules.
Hlaváček, Adam ; Hašek, Jiří (advisor) ; Janderová, Blanka (referee)
eIF5A seems to be involved in both, translation initiation and elongation. It was also reported to affect assembly of P-bodies. Given similarities of P-bodies with stress granules (SGs) we decided to test the role of eIF5A in dynamics of heat-induced SGs and its implications for the cell recovery. For the evaluation of eIF5A function in SGs formation was used the temperature- sensitive (ts) mutant eIF5A-3 (C39Y/G118D) cultivated under permissive temperature 25řC and Rpg1-GFP fusion protein as a marker of SGs. The cells were exposed to robust heat shock at 46řC for 10 minutes. The ability of the mutant cells to recover was tested by propidium iodine staining and colony forming units plating. We found that the eIF5A-3 mutant forms heat-induced SGs more loosely aggregated, indicating that the fully functional eIF5A is necessary for SGs assembly. However, it does not seem to affect the rate of SGs dissolution. Survival tests indicate that eIF5A-3 mutant cells are susceptible to dying in a similar way as WT cells; nevertheless, their ability to resume proliferation is significantly better. We also observed a loss of the ts phenotype of the eIF5A-3 mutant. This loss cannot be explained by reversion of mutated eIF5A sequence into normal. Probable cause lies in the adaptive evolution. Our results indicate role of...
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Force ductility of asphalt binders
Smolka, Zdeněk ; Coufalík, Pavel (referee) ; Dašek, Ondřej (advisor)
The bachelor thesis describes a laboratory characteristics of bituminous binders. There will be described the principle and results of laboratory tests, needle penetration, softening point by ring and ball and force ductility. The tests will be performed on samples of the bituminous binders with different degrees of modification.
|
|
|
Evaluation of Nuclear Fuel Safety and Reliability Using Research Reactors' In-Core Experiments
Matocha, Vítězslav ; Foral, Štěpán (referee) ; Katovský, Karel (advisor)
The aim of this master thesis is to show a connection among nuclear fuel safety, experiments led in research reactors and calculation codes. This thesis focuses on the calculation code Transuranus. There are represented four experiments, which were calculated in Transuranus. The fission gas release, elongation and growth of fuel were particularly monitored. Is is possible to set differences among versions v1m1j09 and v1m3j12 from achieved results, as well as the influence of selected Transuranus parameters on the results, so the thesis may bring new pieces of knowledge for improvement of safety analysis calculation by Transuranus.
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